Partnering opportunity

A Hungarian company producing cyclodextrins is looking for distributors

Summary

A Hungarian pharmaceutical/biotech SME specialized in cyclodextrin uses (development, manufacturing, formulations, analysis, and custom synthesis) is looking for partners. The range of products include all types of cyclodextrins used in pharma and other industrial applications and a wide range of special portfolio (> 100 different types) for research and development. The company is currently open to business co-operations in supplying cyclodextrins through distributors.

Partner expertise sought

Not available

Description

The Hungarian pharmaceutical company is a world-wide recognized and all-round cyclodextrin research and development company, having the longest tradition. The staff of internationally acknowledged experts have been working on the fields of pharmaceutical, cosmetic and food industry, agrochemical, environmental and analytical applications of cyclodextrins. The company has been involved in the development of cyclodextrin for over 40 years and obtained over 120 patents on their production technology and uses. Cyclodextrins, currently manufactured at its site are all made by proprietary processes, used in commercial products and clinical trials worldwide. Currently, there are over 60 products from the widest therapeutic areas and administration routes on the market using altogether 7 different types of cyclodextrins. Since several derivatives have eminent safety record, one can select the right and best performing cyclodextrin for the specific purpose with professional help. Cyclodextrins can be safely used in all typed of administration routes (topical, oral, parenteral, intranasal, etc.) even in high doses, are inert to the human body and excreted unmetabolized. The use of cyclodextrins often propose an alternative solution to existing problems, improving formulations already on the market or to develop bioequivalent versions thereof. This frequently creates new intellectual property and the possibility to patent the technology even for re-discovered molecules. The company has two GMP (Good Manufacturing Practice) facilities, one dedicated to the production of sulfobutylether beta-cyclodextrin (SBECD) in multiple ton scale annually based on an FDA-approved Drug Master File (FDA=Food and Drug Administration). The smaller site is reserved for custom syntheses for early phase clinical studies. The company is looking for expanding the use of cyclodextrins with the help of distributors to all European countries, in particular the ones with strong pharma industries. Type of agreements are flexible, could be either territorial or customer protection based.

Advantages and innovations

Cyclodextrins are able to form inclusion complexes with a wide variety of molecules to improve the intrinsic physicochemical properties of the active pharmaceutical ingredients (APIs). The use of cyclodextrins in pharma and other industries is widespread since these excipients combine the advantages of traditional additives and outperform them in safety and toxicity studies. Thus, cyclodextrins can be used to overcome multiple common challenges in pharmaceutical and other industries, like: • significant solubility enhancement • improvement of chemical stability • increased bioavailability, facilitated delivery • reduced aggregation • moderated irritation or reduced side-effects • maximized safety, complete renal elimination • enables formulation of water-insoluble APIs in all dosage forms • lower API doses can be achieved.

Development stage

Not available

Intellectual Property Rights (IPR)

Not available


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