Partnering opportunity

Minimal invasive right ventricular assist device

Summary

A German university has developed an axial blood pump with an integrated external rotor motor and foldable blades, which, among other things, is characterized by removable fixation, low wear and tear and low heat generation. Thus this pump is suitable for both short-term cardiac support and long-term use. The university offers a technical cooperation and license agreement.

Partner sought

This offer addresses manufacturers of active medical implants in the cardiological field. As a first step, a technical cooperation agreement is offered in order to support the further development of the implant until it is ready for series production. The task of a potential partner is the further development of the system up to the approval of medical devices. The partner should have extensive product and development experience in cardiology. Licensing of the resulting implant or the sale of the industrial property rights is then offered in a second step.

Description

Early introduction of a right ventricular assist device (R-VAD) has been proven beneficial for patients who need acute right heart support. However, most commercially available R-VADs are still associated with complications such as hemolysis, infection and need for anticoagulation. Thus they are only used for short-term application. Some devices provide long-term support, but due to the invasive implantation procedure they are usually offered as a last resort to critically ill patients after all other alternative treatments have been exhausted. Consequently, there is still an unmet clinical need for minimally invasive implantable R-VADs which can be used as bridge-to-recovery as well as destination therapy. A German university has now developed an axial blood pump with an integrated external rotor motor and foldable blades, which, among other things, is characterized by removable fixation, low wear and tear and low heat generation. The invention is based on a foldable conduit-free axial flow pump directly driven by an integrated miniature external-rotor motor. The foldable components include impeller blades, removable fixation structures and a stent. The system can be inserted via peripheral vessels in a collapsed form and is expanded in the pulmonary artery immediately after the pulmonary valve. In the case of bridge-to-recovery application, it can easily be removed due to its robust but removable fixation clips. As a first step, a technical cooperation agreement is offered in order to support the further development of the implant until it is ready for series production. When this is achieved, the licensing of the implant or the sale of the industrial property rights is offered.

Advantages and innovations

In contrast to the well-known minimally invasive systems, this pump is suitable for both short-term cardiac support and long-term use. The system generates higher torque at lower rotational speed and thereby minimizes wear. Additionally, an axial blood pump with foldable blades attached to the rotor of the integrated external rotor motor and a removable fixing option is not known in the state of the art. Other advantages are: - Minimally invasive application - Suitable for bridge-to-recovery or destination therapy - Excellent hemocompatibility

Development stage

Under development/lab tested

Intellectual Property Rights (IPR)

Patents granted


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