Development of fungal biotechnological platforms for the production of natural products by means of synthetic biology
A Spanish biotechnological research organization offers its innovative biotechnological fungal platforms for the production of terpenoid-or peptidic-nature compounds. The advantage of the platforms, versus prokaryotic ones or chemical synthesis, is the production of certain metabolites mainly those naturally occurring in plants. Partners sought are SME,R&D institutions or universities, in order to achieve service agreements or research cooperation agreements to submit to European programmes.
Partner expertise sought
The organization is a Spanish biotechnological private non-profit research institute, founded in 1993, whose main activities are related to molecular biology and microbial biotechnology. The institution keeps close links with industrial research and innovation. The research organization, with strong background as participant in European projects from different calls, offers its expertise focused on fungal biotechnology and genetic engineering to modify metabolic pathways towards the biosynthesis of heterologous or homologous secondary metabolites. This approach is intended to generate custom biotechnological fungal platforms to produce, by means of fermentation, compounds of difficult chemical synthesis such as terpenoid- or peptidic-nature compounds. This technology allows the increasing of the productivity and reducing costs. The biotechnological fungal platforms are especially relevant for the pharmaceutical industry, where the production of certain drugs (such as some naturally occurring in plants of difficult extraction and purification), is only achieved by means of chemical synthesis, being a limiting technology due to the requirement of laborious and expensive protocols. The desired cooperation type would be as member of a European call consortium, where the organization could participate as the developer of biotechnological platforms of industrial interest. After the development of such platforms other partners (e.g. fermentation company) could test them and validate them in terms of yield and the downstream process. Other cooperation sought are services agreement for the development of fungal platforms for the production of natural products of industrial interest.
Advantages and innovations
The main advantage of the platform lays on the development of an innovative technology for the production of natural products, with pharmacological properties and of difficult chemical synthesis, by means of fermentative processes. This production is intended to replace the complex, pollutant and expensive chemical synthesis classical process. For this purpose, fungal microorganisms will be adapted by biotechnological approach for the production of those metabolites. This represents an innovative aspect, since adaptation of heterologous biosynthetic pathways to fungal platforms, so as they produce the metabolite of interest, represents a challenge from the biochemical and genetical points of view. For industry is very interesting this technology for increasing the productivity and reducing costs.
Intellectual Property Rights (IPR)
Register your interest
How it works
- Tell us about yourself
- We’ll discuss with you
- We put the right partners in touch
EEN help you find the right partner, rather than you going it alone.
Our role is to review and collate the most suitable submissions, and then send them to the client who posted the opportunity. We consult with you, and the client, to make the process professional and easy.
These are live opportunities. Your registration of interest on the site is just like a professional approach to a business at a networking event. To stand the best chance of success, make your submission really sing. Sell why the client who posted the opportunity should work with you. Excite them. Ask questions. Try and avoid copy and pasting words from elsewhere.
Once the client has chosen their partner, we'll introduce them over email and keep in touch with both parties to see how it's going. Sometimes things progress quickly. Sometimes because of changing priorities for either party, things progress slowly, but you never know - your next big business break could start right here.
First we need to check you’re human.
Thank you for verifying your email. We have sent you a confirmation email containing a 6 digit verification code to unlock the form below