Proteomics service allowing genome analysis
A Spanish biotechnological institute offers its proteomics facilities for the differential expression analysis of proteins (microorganism, animal, vegetal or humans). The approach used is based on bidimensional gels and subsequent identification by mass spectrometry (matrix assisted laser desorption, "time of fligh” - MALDI TOF/TOF). This approach is highly recommended for proteomics analysis based on non-public genomes. Industrial and academic researchers are sought for services agreements.
Biotech companies, academic research groups and any other organization interested in proteomics analysis (industrial microorganisms, model organisms and other) are sought in order to establish a service agreement.
The organization is a Spanish biotechnological private non-profit research institute, founded in 1991, whose main activities are related to molecular biology and microbial biotechnology. The institution keeps close links with industrial research and innovation. The team covers several techniques and counts with a long experience in European funded projects. The center has a strong track record of analyzing proteomics based on gels stained with visible (coomassie, silver) and fluorescent dyes (two-dimensional difference gel electrophoresis (DIGE), Pro-Q Diamond, SYPRO Ruby…), as well as 2 dimensional (2D)-western detection. Its know-how covers from protein sample preparation, purification, cleaning, 1 dimensional (1D) and 2D analysis, and protein identification. The center facilities allow the integration of non-public genomes in a private database under a non-disclosure agreement, which is a functional advantage for enterprises focused on mutant analysis and metabolites production enhancement. Proteomics is allowing the complementation of other omics analyses (genomics, transcriptomics and metabolomics), which are easily integrated in the center pipeline due to its experience in production of different industrial-relevant metabolites. The based on bidimensional gels and subsequent identification by mass spectrometry (MALDI TOF/TOF) is highly recommended for proteomics analysis based on non-public genomes under a non-disclosure agreement. Biotech companies, as well as academic research groups, interested in the study of the differential expression analysis of proteins (microorganism, animal, vegetal or humans) can benefit from the proteomics analysis service thought services agreement.
Advantages and innovations
The institute counts with a long experience in molecular microbiology and also in omics techniques. The experience of the researchers that provide the proteomic service is an advantage based on the common use of bioinformatics procedures, but also for the experience gained as principal investigators of national and European projects. This broader experience serves to offer a service focused on the needs of the costumers. The innovative aspect of the proteomics service for genome analysis is based on mass spectrometry that allows the identification and relative quantification of thousands of proteins in a single assay.
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